New research indicates that overexpression of the transcription factor SOX9 restores the sensitivity of mouse and human melanomas to the anticancer agent retinoic acid, thereby stopping tumor growth. The authors suggest that a combined therapeutic strategy, increasing the expression of SOX9 while simultaneously treating with RA, may provide new hope to effectively treat RA-resistant cancers such as melanoma.
Full article >>
Wednesday, March 11, 2009
Transcriptional Factor SOX9 Renders Melanomas Sensitive To Retinoic Acid And Stops Tumor Growth
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment