Angiogenesis Inhibitor Improves Brain Tumor Survival By Reducing Edema

The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema -- the swelling of brain tissue -- and not from any direct anti-tumor effect. A new report describes how treatment with the experimental drug cediranib reduced edema and improved survival in three mouse models of glioblastoma.
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