Breast Cancer Hormone Receptor Status And Risk Of A Second Primary Tumor

Women with hormone receptor negative first tumors have twice as much risk for developing a second breast cancer as women with HR-positive tumors, according to a new study.
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New Location Found For Regulation Of RNA Fate

Thousands of scientists and hundreds of software programmers studying the process by which RNA inside cells normally degrades may soon broaden their focus significantly. Researchers have discovered that the RNA degradation, which, when improperly regulated can lead to cancer and other diseases, can be launched in an unexpected location.
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Virus Linked To Some Cases Of Common Skin Cancer

A virus discovered in a rare form of skin cancer has been found in people with squamous cell carcinoma, a common skin cancer. Researchers identified the virus in more than a third of 58 SCC patients and in 15 percent of their tumors. Virus found in tumor cells had a mutation that could enable it to integrate into the host cell DNA, suggesting that the virus might help cause some cases of SCC.
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Altered micriobiome prevalent in the diseased esophagus

Gastroesophageal reflux diseases , or GERD, affects about 10 million people in the United States, yet the cause and an unexpected increase in its prevalence over the last three decades remains unexplainable. Now, researchers have discovered that GERD is associated with global alteration of the microbiome in the esophagus. The findings, reported in the August 1, 2009 issue of Gastroenterology, may provide for the foundation for further study of the condition as a microecological disease with new treatment possibilities.
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Common diabetic therapy reduces risk of pancreatic cancer, study finds

Taking the most commonly-prescribed anti-diabetic drug, metformin, reduces an individual's risk of developing pancreatic cancer by 62 percent, according to research from The University of Texas M. D. Anderson Cancer Center, published in the Aug. 1 issue of Gastroenterology.
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Hunt For The Blood Test To Determine Melanoma Survival Rates

New research will be breaking new ground in the search for a simple blood test that could tell whether a patient with melanoma has the condition in an aggressive form. Melanoma is the most aggressive form of skin cancer. Staging, which involves determining the size of the tumor and its extent of spread, is the best predictor of whether a patient will succumb to disease or survive.
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Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months.
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